1. Buffer pool too small  2. Inadequate Disk I/O subsystem  3. I/O bottleneck  4. Missing Indexes  5. Low index usage like  poorly design indexes  6. Temp DB contention  7. Data and Log file are on same drive  8. Slow network  9. Client side performance issue  10. Query plan not updated or poor  11.If Update statistics not updated  12.Memory configuration setting not done properly  13.Lock page memory not configured with sql service user.  
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